Immunology / IL-23 inhibitor
Skyrizi costs $5–$300/month.
Skyrizi (risankizumab) has a manufacturer list price near $24,000/year ($2,000/dose) and is classified as a Tier 4 or 5 specialty drug on most plans, with the AbbVie Complete Savings Program capping eligible commercially insured patients at $5/month.
Estimates only. Verify with your pharmacy and insurer before filling. Not medical, financial, or insurance advice.
Where to fill
Skyrizi prices by source
Sources: manufacturer published pricing · Costplus Drug Co. catalog · Walmart $4 list · GoodRx public pricing.
Commercial insurance
Your cost by plan
Tier from each carrier’s 2026 formulary — source documents linked on each plan card below. Use the calculator above for a personalized estimate based on your deductible state.
Blue Cross Blue Shield Employer PPO
Illinois Blue Choice PPO
Tier 4PA required
$5–$300/mo (varies)
See formulary ↗Blue Cross Blue Shield Employer HMO
Texas Blue Advantage HMO
Tier 4PA required
$5–$300/mo (varies)
See formulary ↗Anthem Marketplace Silver
Silver 4500/40 Marketplace
Tier 4PA required
$5–$300/mo (varies)
See formulary ↗Blue Shield of California Employer HMO
Access+ HMO
Tier 4PA required
$5–$300/mo (varies)
See formulary ↗Independence Blue Cross Employer PPO
Personal Choice PPO
Tier 4PA required
$5–$300/mo (varies)
See formulary ↗Ambetter (Centene) Marketplace Silver
Balanced Silver
Tier 4PA required
$5–$300/mo (varies)
See formulary ↗Kaiser Permanente Employer HMO
Mid-Atlantic HMO (MD/VA/DC)
Tier 4PA required
$5–$300/mo (varies)
Carrier page ↗CareFirst BCBS Employer HMO
BlueChoice HMO (DC/MD/VA)
Tier 4PA required
$5–$300/mo (varies)
See formulary ↗Savings program
AbbVie Complete Savings for Skyrizi
What you pay
$5/mo
Subject to eligibility · 30-day supply
Eligibility
- Commercial insurance covering Skyrizi
- Not eligible: Medicare, Medicaid, TRICARE, VA
- US residents 18+
FAQ
Skyrizi cost questions
How much does Skyrizi cost with insurance?
Skyrizi is a specialty drug — most commercially insured patients pay $5–$300/month with the AbbVie Complete Savings Card. Without the savings card, post-deductible costs can range $400–$1,200/month depending on plan tier and coinsurance structure.
What is the AbbVie Complete Savings Card for Skyrizi?
The Skyrizi Complete Savings Program caps eligible commercially insured patients at $5/month, with up to $14,000 in annual savings. Patients with Medicare, Medicaid, or no insurance are not eligible.
Is there a generic or biosimilar for Skyrizi?
No. Skyrizi (risankizumab) is biologic and there are no FDA-approved biosimilars as of 2026. The manufacturer savings card is the primary path to reduce out-of-pocket cost.
How does Skyrizi compare to Humira?
Skyrizi (IL-23 inhibitor) and Humira (TNF-alpha inhibitor) treat overlapping conditions like psoriasis and Crohn's disease but work via different mechanisms. Skyrizi is dosed quarterly after induction; Humira is dosed every 1–2 weeks. Cost paths and coverage differ — verify both with your plan.
Why is Skyrizi so expensive?
Skyrizi is a biologic drug manufactured from living cells, with high R&D and production costs. The ~$24,000/year list price reflects standard specialty biologic pricing in the US, with manufacturer savings cards designed to bring insured patient out-of-pocket toward $0.
Does insurance cover Skyrizi?
Most commercial plans cover Skyrizi at Tier 4 or Tier 5 (specialty), with prior authorization typically required. The insurance breakdown above shows the seven plans we track and their typical PA requirements.
What if my insurance denies Skyrizi?
If your prior auth is denied, options include: appealing with your prescriber and documentation of prior treatment failures, switching to a covered biologic (e.g., Humira, Stelara), or using the AbbVie Patient Assistance Program if you have limited financial resources.
Where can I fill Skyrizi?
Skyrizi is typically dispensed through specialty pharmacies rather than retail chains. Your plan will direct you to a specific specialty pharmacy partner; AbbVie's Skyrizi Complete program coordinates shipping and savings card application.
Related medications
See how Skyrizi compares
Data sources
Source URLs for Skyrizi have not yet been manually verified. Estimates above are modeled from public pricing patterns and manufacturer-published list prices.
- • Manufacturer published pricing pages
- • NADAC National Average Drug Acquisition Cost
- • Carrier-published formulary tiers (where known)
- • Cost Plus Drugs / mail-order public pricing
- • FDA Orange Book (generic availability)